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How Do Farmers Grow Seedless Grapes?
(The old way farmers grew seedless grapes.) Farmers use a special liquid to make grapes seedless. This liquid has a plant hormone called Gibberellin in it. The Gibberellin is formed from a fungus. The buds on the grape vine are dipped in this substance two weeks before flowers appear. When the flowers appear, they are dipped again. This is how the grapes are seedless.

This is what the grapes look like before their flowers bloom. This is when they are dipped in the special substance for the first time.
How Grapes are Now Made Seedless
Most grapes no longer come from seeds. They come from cuttings instead. A piece of a vine or branch is cut off, dipped in rooting hormone and then placed in dirt that is moist. This allows the roots and leaves form. Because they come from cuttings, new grapevines are basically just clones of the vine they were cut from. Seedless grapes actually do contain seeds at some point, but a genetic error is what prevents the seeds from forming a hard cover.
Question and Answer

Q. What are the small dots of different colored flesh that are sometimes found in seedless grapes? These are actually seeds. The seeds begin to develop, but because of a genetic mutation, the seeds do not form a hard outer coat.

Q. How long have grapes been cultivated for? Since at least 6000 B.C.

Q. Where were grapes first cultivated? In the Black Sea region. Grapes in not make it to Italy until around 2000 B.C.

Q. When did the Italians start making wine? Around 1500BC is when the vine yards were introduced to Italy.

Sources: A Child's First Library of Learning. Time-Life Books Science Starter. Alexandria, Virginia 1989.